紹介
"Biotargets of Cancer in Current Clinical Practice" presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
目次
Ch. 1- Central Nervous System Tumors Paolo Aloisi Francesco Martella Davide Cerone Giampiero Porzio Ch. 2- Head and Neck Tumors Keith D. Hunter Robert Bolt Ch. 3- Thyroid Cancer Laura D. Locati Angela Greco Maria Grazia Borrello Maria Luisa Carcangiu Paolo Bossi Roberta Granata Lisa Licitra Ch. 4- Targeted Therapies for Non-Small Cell Lung Cancer Giulio Metro Lucio Crino Ch. 5- Non-Hodgkin Lymphomas Roberta Zappasodi Massimo Di Nicola Ch. 6- Leukemias Lia Ginaldi Massimo De Martinis Ch. 7- Breast Cancer Nadia Rucci Luca Ventura Anna Teti Ch. 8- Esophago-Gastric Cancer Alex M. Reece-Smith Simon L. Parsons Sue A. Watson Ch. 9- Colorectal Cancer David Church Rachel Midgley David Kerr Ch. 10- Hepatocellular Carcinoma Yasunori Minami Masatoshi Kudo Ch. 11- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma Laura S. Schmidt Ch. 12- Bladder Cancer Andrea Tubaro Daniele Santini Cosimo De Nunzio Alice Zoccoli Michele Iuliano Ch. 13- Biomarkers in Prostate cancer Mauro Bologna Carlo Vicentini Ch. 14- Ovarian Cancer Jessica Wangui Oribabor Allison Ambrosio Cesar M. Castro Michael J. Birrer Ch. 15- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer Annekathryn Goodman Leslie S. Bradford Leslie A. Garrett Ch. 16- Biotargets in Sarcomas: The Past, Present and a Look into the Future Vivek Subbiah Razelle Kurzrock Ch. 17- Melanoma and other skin cancers Kim H.T. Paraiso Jobin K. John Keiran S.M. Smalley Ch. 18- Molecular pathology of cancer metastasis: suggestions for future therapy Adriano Angelucci Edoardo Alesse Ch. 19- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools Marilena V. Iorio Patrizia Casalini Claudia Piovan Luca Braccioli Elda Tagliabue