目次
I. INTRODUCTION 1. Introduction - Henry deF. Webster II. STRUCTURE OF THE PERIPHERAL NERVOUS SYSTEM 2. Gross Anatomy of the PNS - Ernest Gardner & Richard P. Bunge (No change/will use PN3 version) 3. Microscopic Anatomy of the PNS - C.H. Berthold, J. Fraher & R. H. M. King III. FUNCTION OF THE PERIPHERAL NERVOUS SYSTEM 4. Channel Function in Axons and Sheath Cells -S. Y. Chiu 5. Nerve Excitability Measures: Biophysical Basis and Use in the Investigation of Peripheral Nerve Disease - Matthew C. Kiernan, David Burke & Hugh Bostock 6. The Muscle Spindle - R. W. Banks 7. The Golgi Tendon Organ - J. Scott 8. The Peripheral Sensory Nervous System: Dorsal Root Ganglion Neurons - Sally N. Lawson 9. The Pupil - James J. Corbett 10. 11. Neurologic Control of Cardiac Function - David Paterson & John Coote 12. Neurobiology of Autonomic Peripheral Ganglia - David Kreulen 13. Neurobiology of the Enteric Nervous System - Jackie D. Wood 14. Autonomic and Somatic Systems to the Anorectum and Pelvic Floors - Adil E. Bharucha & Christopher Klingele 15. Autonomic Systems to the Urinary Bladder & Sexual Organs - William C. de Groat & August M. Booth 16. Sympathetic nerves and control of blood vessels to human limbs - Michael J. Joyner, Paul M. VanHoutte, John R. Halliwill & John T. Shepherd IV. NEUROBIOLOGY OF THE PERIPHERAL NERVE SYSTEM 17. Molecular Signaling in Schwann Cell Development - R. Mirsky & K. Jessen 18. Growth Factors of the PNS - Anthony Windebank 19. Axonal Flow - W. Stephen Brimijoin 20. Myelination - O. Suter & R. Martini 21. The Control of Axonal Caliber - John W. Griffin & Ahmet Hoke 22. Guidance of Axons to Targets in Development and in Disease - Frank Bradke 23. Aging of the PNS - T. Cowen & R.H.M. King 24. Oxidative Stress and Excitatory Neurotoxins - Phillip A. Low 25. Transgenic Models of Nerve Degeneration - R. Martini V. NEUROIMMUNOLOGY OF THE PERIPHERAL NERVOUS SYSTEM 26. Introduction to Immune Reactions in the PNS - Hans-Peter Hartung, Guido Stoll & Klaus Toyka 27. Peripheral Nerve Antigens - Hugh J. Willison, Norman A. Gregson, Graham M. O'Hanlon & Richard A. C. Hughes 28. Experimental Autoimmune Neuritis (EAN) - Ralf Gold, Guido Stoll, Bernd C. Kieseier, Hans-Peter Hartung & Klaus Toyka 29. Fundamentals of Immune Therapy - J.D. Pollard, Richard Hughes & Peter Hartung VI. FUNCTIONAL COMPARTMENTS AND NERVE-FIBER ENVIRONMENT 30. The Blood Nerve Barrier - Ananda Weerasuriya 31. Nerve Blood Flow and Nerve Fiber Microenvironment - Phillip McManis & Phillip A. Low VII. PATHOLOGY 32. Pathology of Peripheral Neuron Cell Bodies - Michale J. Groves & Francesco Scaravilli 33. Pathologic Alterations of Nerves - Peter J. Dyck, P. J. B. Dyck & JaNean Engelstad 34. Pathology of the Neuromuscular Junction - Andrew G. Engel 35. Pathology and Quantitation of Cutaneous Innervation - William R. Kennedy, Justin C. McArthur, Michael J. Polydefkis & Gwen Wendelschafer VIII. NERVE CONDUCTION AND ELECTROMYOGRAPHY 36. Nerve Conduction and Needle Electromyography - Jun Kimura 37. Nerve Tests Expressed as Percentiles, Normal Deviates and Composite Scores - Peter J. Dyck, Peter C. O'Brien, Jenny Davies, Christopher J. Klein & P. James B. Dyck 38. Single Fiber Electromyography - Erik Stalberg & J. Trontelj 39. Single-unit Recordings of Afferent Human Peripheral Nerves by Microneurography - Erik Torebjork & Martin Schmelz 40. Compound Action Potential of Sural Nerves in Vitro - Edward H. Lambert & Peter J. Dyck(No change/will use PN3 version) IX. QUANTITATING SYMPTOMS, IMPAIRMENTS AND OUTCOMES 41. Quantitating Neuropathic Symptoms, Impairments and Outcomes - Peter J. Dyck & Richard A. C. Hughes 42. Health Outcomes and Quality of Life - Ann Jakoby 43. Quantitation of Sensory Abnormality - Peter J. Dyck, Peter C. O'Brien, David M. Johnson Christopher J. Klein & P. James B. Dyck 44. Quantitation of Muscle Contraction & Strength - Kenton R. Kaufman 45. Quantitation of Autonomic Impairment - Phillip Low & C.J. Mathias X. DISEASES OF THE PERIPHERAL NERVOUS SYSTEM Part A. Differential Diagnoses and Epidemiology 46. Clinical Patterns - Philip Thompson & P. K. Thomas 47. Differential Diagnoses of Polyneuropathy - Ian A. Grant, Timothy J. Benstead & Peter J. Dyck 48. Epidemiologic Approaches to Peripheral Neuropathy - James P. Burke & L. Joseph Melton, III Part B. Diseases of Cranial Nerves 49. Diseases of the Third, Fourth, and Sixth Cranial Nerves - Jacqueline A. Leavitt & Brian R. Younge 50. Diseases of the Fifth Cranial Nerve - Richard A. C. Hughes 51. Diseases of the Seventh Cranial Nerve - Caroline M. Klein 52. Diseases of the Eighth Cranial Nerve - Linda M. Luxon & Doris Bamiou 53. Diseases of the Ninth, Tenth, Eleventh, and Twelfth Cranial Nerves - C. Mathias & P. K. Thomas Part C. Diseases of Spinal Cord, Spinal Roots, and Limb Girdle Plexuses 54. Myelopathies Affecting Anterior Horn Cells and Centrally Directed Afferent Axons in Posterior Horns and Columns - Caroline Klein & Annabel Wang 55. Diseases of Spinal Roots - Colin Chalk 56. Mechanical Compression, Traction, Electrical Radiation and Neoplastic Infiltration of the Brachial Plexus - Asa Wilbourne 57. Diseases of Spinal Cord, Spinal Roots, and Limb-Girdle Plexuses - Michael Donaghy Part D. Neuropathy Due to Compression, Entrapment or Physical Injury 58. Mechanisms of Nerve Injury from Compression, Entrapment, Traction and Ischemia - Ted Burns & Peter J. Dyck 59. Mechanisms of Repair After Traumatic Injury - Susan Hall 60. Median Neuropathy - J. Clarke Stevens 61. Upper Limb Neuropathies: suprascapular, axillary, nerve to serratus anterior, radial and ulnar - Asa Wilbourne 62. Lower Limb Neuropathies - Asa Wilbourne 63. Operating on Peripheral Nerves - Rolfe Birch Part E. Sporadic Motor Neuron Disease 64. Sporadic Motor Neuron Degeneration - Nigel Leigh Part F. Basis of Inherited Disease 65. Mendelian and Mitochondrial Inheritance, Gene Identification, and Clinical Testing - Virginia V. Michels, Stephen N. Thibodeau & Erik C. Thorland 66. Transgenic Models of Inherited Neuropathy - Clare Huxley & Andrea Roberterson Part G. Inherited Motor Neuron Degeneration 67. Transgenic Models of ALS - Eric Sorenson 68. Inherited Motor Neuron Degeneration - Nigel Leigh 69. Hereditary Motor Neuropathies (Spinal Muscular Atrophies) - Peter de Jonghe Part H. Hereditary Motor and Sensory Neuropathies 70. Principles of Classifications, Clinical Syndromes - Michael Shy, Peter J. Dyck, Phillip F. Chance, James R Lupski & Christopher J. Klein 71. Disorders Related to PMP22 Mutations - James R. Lupski & Phillip F. Chance 72. The Hereditary Motor and Sensory Neuropathies (HMSN) 73. Related to MPZ (P0) Mutations - Michael E. Shy 74. Disorders Related to EGR 2 Mutations - Laura E. Warner & James R. Lupski 75. Molecular Genetics of HMSN II (CMT 2)- Christopher J. Klein & Peter J. Dyck 76. Hereditary Brachial Plexus Neuropathy - Christopher J. Klein & Anthony J. Windebank 77. Autosomal Recessive HMSN - Anneke Gabr??ls-Festen & P. K. Thomas 78. X-Linked HMSN - Steve Scherer 79. Multiple Endocrine Neoplasia, Type 2B - J. Aidan Carney Part I. Hereditary Sensory and Autonomic Neuropathies 80. Clinical, Pathologic Classification, and Molecular Genetics - Christopher J. Klein, Robert H. Brown & Peter J. Dyck Part J. Inborn errors of Metabolism With Peripheral Nerve Involvement 81. Lysosomal and Peroxisomal Disorders - P. K. Thomas & Hans Goebel 82. Porphyria - A. J. Windebank 83. Fabry Disease - Roscoe O. Brady & Raphael Schiffmann 84. Tangier Disease and Neuropathy - Mason Freeman & Gilmore O'Neill 85. Hereditary Amyloid Neuropathy - M. Reilly 86. Mitochondrial Disorders - Michael Hanna Part K. Neuropathy Associated with Systemic Disease 87. Diabetic Polyneuropathy - P.K. Thomas, D. Tomlinson & G. Llewelyn 88. Diabetic Radiculoplexus Neuropathies - P. James B. Dyck & J. Clarke Stevens 89. Neuropathies Associated With Renal Failure, Hepatic Disorders, Chronic Respiratory Disease and Critical Illness - Douglas W. Zochodne 90. Neuropathy in Diseases of Thyroid and Pituitary Glands - John Pollard Part L. Nutritional and Vitamin Deficiencies 91. Nutritional and Vitamin Deficiency - David Saperstein & Richard Barohn 92. Myeloneuropathies - Gustavo C. Roman Part M. Infections 93. Leprosy - Thomas D. Sabin, Thomas R. Swift & Robert R. Jacobson 94. Lyme Borreliosis - Gerard Said 95. Herpes Simplex and Zoster - Donald Gilden & Kenneth Tyler 96. Peripheral Neuropathies in HIV Infection - Ahmet Hoke & David R. Cornblath 97. Diphtheritic Polyneuropathy - David Pleasure & Albee Messing 98. Parasitic Infections - Sudha Pottumarthy & Thomas Fritsche Part N. Inflammatory and Immune 99. Antibodies to Nerve Components and Neuropathy - A. Pestronk & Glenn Lopate 100. AIDP - John W. Griffin 101. CIDP - Angelika F. Hahn, Hans-Peter Hartung & Peter J. Dyck 102. Neuropathy Associated with the Monoclonal Antibodies - Robert A. Kyle & Peter J. Dyck 103. Multifocal Motor Neuropathy and Persistent Conduction Block - H. J. Willison & Bruce V. Taylor 104. Brachial Plexus Neuropathy - Guillermo A. Suarez 105. Nonmalignant Inflammatory Sensory Polyganglionopathy - Benn E. Smith, Anthony J. Windebank & Peter J. Dyck 106. Cryptogenic Sensory Polyneuropathy - Ian A. Grant 107. Neuropathies with Systemic Necrotizing Vasculitis - John T. Kissel & Jerry R. Mendell 108. Neuropathies and Microvasculitis - P. James B. Dyck 109. Sarcoid Neuropathy - Gerard Said & Catherine Lacroix Part O. Peripheral Neuropathy Associated with Malignancy, etc. 110. Amyloidosis and Neuropathy - Robert A. Kyle, John J. Kelly & Peter J. Dyck 111. POEMS Syndrome (Osteosclerotic Myeloma)- Angela Dispenzieri & Guillermo A. Suarez & Robert A. Kyle 112. Paraneoplastic Neuropathy - James McLeod & J. Spies 113. Peripheral Neuropathy Associated with Lymphoma, Leukemia and Myeloproliferative Disorders - E. Peter Bosch, Thomas M. Habermann & Ayalew Tefferi Part P. Neuropathy Associated With Industrial Agents, Metals and Drugs 114. Industrial Agents - Alan Berger & Herbert Schaumburg 115. Metal Neuropathy - A.J. Windebank 116. Pharmaceutical Agents - Steve Herskovitz & Herb Schaumberg Part Q. Tumors 117. Peripheral Nerve Tumors - Caterinia Giannini Part R. Management 118. Management with Acute Neuromuscular Disease in the Intensive Care Unit - Eelco Wijdicks 119. Physical Medicine & Rehabilitation - Mary Dombovy 120. Mechanisms and Pharmacologic Management of Neuropathic Pain - Michael C. Rowbotham 121. Management of Autonomic Failure - Phillip A. Low 122. Management of Cardiovascular Failure - Roy L. Freeman 123. Management of Gut Dysmotility - Michael Camilleri & Adil Bharucha 124. Peripheral Neuropathies in Infants and Children - Ted M. Burns, Monique M. Ryan, Basil T. Darras & H. Royden Jones